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Review paper

The role of Epstein-Barr virus in the pathogenesis of NasoPharyngeal Carcinoma
March 13, 2025 CDT
The role of Epstein-Barr virus in the pathogenesis of NasoPharyngeal Carcinoma
Kristie LuAyman Reffai

The paper reviews the effect of the Epstein-Barr virus on the development of NasoPharyngeal Carcinoma. Diagnostic detection tools that incorporate Machine Learning are suggested to minimize false positive rates.

The Orexin/Hypocretin system and its role in the etiology of psychiatric deficits following Traumatic Brain Injury
March 05, 2025 CDT
The Orexin/Hypocretin system and its role in the etiology of psychiatric deficits following Traumatic Brain Injury
Nina Papamichail

This paper investigates the mechanisms by which Traumatic Brain Injury associated abnormal orexin levels and receptor expression cause psychiatric symptoms such as insomnia, daytime sleepiness, major depressive disorder or anxiety.

CAR T-cell therapies: A Comparison of strategies for Glioblastoma Multiforme treatment
March 02, 2025 CDT
CAR T-cell therapies: A Comparison of strategies for Glioblastoma Multiforme treatment
Shwetha Sundar

This review examines the mechanisms, advantages and limitations of General, SynNotch and Armored CAR T-cell therapies for treating Glioblastoma Multiforme. A novel 'Elapsed time' gene circuit is proposed.

Optimizing Induced Pluripotent Stem Cells stability and reprogramming: bridging regenerative medicine and cancer treatment through proposed Antibody-Transcription Factor Conjugates
February 19, 2025 CDT
Optimizing Induced Pluripotent Stem Cells stability and reprogramming: bridging regenerative medicine and cancer treatment through proposed Antibody-Transcription Factor Conjugates
Savya Agarwal

This paper proposes that Antibody-Transcription Factor Conjugates be developed as a novel therapy that can reprogram cancer cells into pluripotent-like non-tumorigenic phenotypes and inhibit their subsequent malignant recurrence.

February 09, 2025 CDT
Digital solutions for adolescent homelessness: a review of health and technological interventions
Congjia YangJeff Karabanow

This study presents a comprehensive overview of existing digital interventions for homeless youth. It examined adolescent homeless user behaviors, engagement patterns, and attitudinal surveys toward these Technology Based Interventions.

December 03, 2024 CDT
Impact of adolescent dance participation on the development of disordered eating habits
Selina Xi

This paper reviews and identifies the risk factors contributing to disordered eating in adolescent dancers and its development into habit over time. Several mitigation strategies are proposed and discussed.

Exploring the role of biological factors in skeletal muscle tissue engineering
November 20, 2024 CDT
Exploring the role of biological factors in skeletal muscle tissue engineering
Kaan Erdem

The effects of biological factors, the use of bacteriophages to modulate gut bacteria, and incorporating M2 macrophages into tissue constructs are discussed in the context of skeletal muscle tissue engineering.

Evaluating the feasibility of legally binding election manifestos
November 02, 2024 CDT
Evaluating the feasibility of legally binding election manifestos
Samridhi Sharma

This study argues against making election manifestos legally enforceable due to significant limitations, proposing instead a reformed approach to manifesto transparency through voluntary and impartial review mechanisms.

The effect of different anesthetic drugs on the incidence of emergence delirium or agitation in pediatric surgeries
October 30, 2024 CDT
The effect of different anesthetic drugs on the incidence of emergence delirium or agitation in pediatric surgeries
Sriyanka Damarla

Propofol, ketamine and/or remimazolam, in combination with sevoflurane were the most effective at reducing the incidence of Emergence delirium and Emergence Agitation in post-operative tonsillectomy and adenoidectomy patients.

The effect of the ketogenic diet in increasing and/or restoring fertility in PolyCystic Ovarian Syndrome (PCOS) patients
September 13, 2024 CDT
The effect of the ketogenic diet in increasing and/or restoring fertility in PolyCystic Ovarian Syndrome (PCOS) patients
Muskaan CM Iyer

The Ketogenic diet's effectiveness in PCOS patients was quantified by efficacy, comparison with other therapies and its caloric and metabolic sustainability over a period long enough to restore fertility.

August 02, 2024 CDT
Analysis of the therapeutic strategies used to treat Amyotrophic Lateral Sclerosis caused by TDP-43 aggregation and/or mislocalization
Sonya Sar

This review focuses on analyzing the benefits and limitations of the therapeutic strategies used to treat ALS caused by dysregulated TDP-43 homeostasis and identifying methods to target this proteinopathy.

July 27, 2024 CDT
Mind over Matter: Flexing cognitive muscles through exercise, training, and dieting to combat age-related cognitive decline
Angelina Xu

This paper found that cognitive training, physical exercise and a healthy diet; individually, and together were able to significantly reduce or prevent age-related cognitive decline in healthy older individuals.